Advanced PainCare helps you get back to your active life.

Pain is disruptive. It keeps you from the things you love and can be a constant source of worry. Everyday tasks like carrying groceries, washing your car or just walking up the stairs can become difficult if you are in pain. Pain can keep you from playing with your children or grandchildren. It can reduce your productivity at work. It can even keep you from work altogether.

At Advanced PainCare, we offer a patient-centric approach to helping you reduce and eliminate your pain and get back to a normal life. Our dual-board-certified pain specialists listen to your needs and tailor a plan specific to your pain. That’s the first and most important step in your recovery.

Our doctors always put patients first. We offer the most advanced nonsurgical and minimally invasive treatments, which allow many patients to avoid evasive surgery and/or large doses of medication.


The Providers
Jean Louise Santo, MD

I decided to go to medical school because no other profession came close for me. I see how pain affects people, their families and their lives. There was never any doubt what direction I would take once entering into medical practice. I made a promise that I would always listen to my patients and do everything possible to help make a difference in their lives. One of the things my patients often comment about is how I listen to them and make them feel cared for.”


Board-Certified: American Board of Anesthesiology

Board-Certified: American Board of Pain Medicine

Certified: Certified in age management medicine by the Cenegenics Education and Research Foundation.

Fellowship training: Pain Medicine, Medical College of Georgia, Augusta, GA

Residency: Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, PA

Internship: General Surgery, Lehigh Valley Hospital Center, Allentown, PA

Medical School: Hahnemann University School of Medicine, Philadelphia, PA

Memberships: American Academy of Pain Medicine, American Society of Interventional Pain Physicians, International Spine Intervention Society, Pennsylvania Medical Society, Cumberland County Medical Society Researcher, author & presenter.

Appointments: Medical Director for Interventional Pain Management at PinnacleHealth, Harrisburg, PA and Pain Management physician for the PinnacleHealth Spine Institute.


Jamie Shirey, CRNPJamie Shirey

“As a nurse at the bedside, I quickly realized the impact that pain had on every aspect of a patient’s life. When I became a Nurse Practitioner and had the opportunity to work in Pain Management the decision was easy. There is nothing more satisfying than being able to help relieve pain so that my patients can get back to enjoying their lives.”


Board Certified: American Association of Nurse Practitioner: Family Nurse Practitioners

Master’s of Science in Nursing: Millersville University, Millersville, PA

Bachelor’s of Science in Nursing: Drexel University, Philadelphia, PA

Associate Degree in Nursing: Harrisburg Area Community College, Harrisburg, PA

Pain Management Training: University of Maryland Shock Trauma Center, Baltimore, MD


Cynthia Maki, MS, RD, Dieticianmaki
“Most people know that proper diet can reduce the risk of chronic diseases such as obesity and diabetes. But did you know that diet can also reduce pain? Your own body has an amazing capacity to heal itself if nourished with the right foods. Modern medicine works better when coupled with good nutrition. Inflammation and the pain associated with it can be reduced by eating an anti-inflammatory, nutrient rich diet. My goal is not to impose a short-term meal plan but to begin to change the way you think about food and its impact on your health and well-being.”

Cynthia is a Registered Dietician who has personal experience in reducing pain associated with arthritis via dietary changes. She is knowledgeable about weight management, food sensitivities and the impact of food on inflammation. Rather than a “one diet fits all” approach, Cynthia assesses each of her clients individually and bases her recommended nutrition strategies on their personal needs.

Graduate Degree: Master of Science Degree in Nutrition from University of Tennessee

Undergraduate Degree: Bachelor of Science Degree in Organic Chemistry from Gannon University

Experience: 10 years as clinical dietician and 20 years in Public Health promoting and educating in health and nutrition.


Compassionate, comprehensive care for your pain

Our mission at Advanced PainCare is to get patients suffering from pain back to their active lives as quickly as possible. To help every patient the best we can by listening and creating a treatment plan specifically tailored to their needs. To provide an unmatched level of care to each and every patient.


Insurance Participants
We accept a variety of different Insurance Providers



“Dr. Santo is always knowledgeable about different types of options and explains each in a way that a patient can understand. She listens to her patients’ needs and treats them as individuals.I have seen this as a patient and as a loved one was being treated by her as well.”

“Everyone is very professional, friendly and provides compassion and care for your health issues.”

“Dr. Jean Santo is the foremost medical doctor in her field in the entire world.”

“My overall experience with Advanced PainCare from the first time I spoke to them on the phone has been great. From check in to check out the staff is pleasant and knowledgeable. I have already recommended this practice to a friend.”

“Thank you so much for taking such excellent care of me and relieving me of pain. I truly appreciate all your care and also accommodating me. God bless you.” -N.P

“Dr. Santo and her staff were wonderful!” -R. M.

“Please know that I sincerely appreciate your skill and compassion.” -E.B

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